PD-1 Blockers
نویسنده
چکیده
Nivolumab and pembrolizumab are monoclonal antibodies that block the programmed death-1 receptor (PD-1, CD279), resulting in dis-inhibition of tumor-specific immune responses. Both are recently approved for use in the treatment of metastatic melanoma, and nivolumab as well for non-small cell lung cancer.
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عنوان ژورنال:
- Cell
دوره 162 شماره
صفحات -
تاریخ انتشار 2015